The two major things that all people are searching for in life are security and significance. Security is the understanding that I am unconditionally loved and significance means that my life has value and meaning.
Most of the time we are searching for both of these needs in all of the wrong places. We try to find unconditional love in human relationships that all inevitably fail us to some degree and cause pain.
Then we look to our career, church and children to give us the meaning and validation in life that we so desperately need. Here again although all of these are quote good things and can give us some degree of significance they to in the end leave us wanting more.
All human relationships are important and being successful in every area of our lives should be our goal. However, the major truth here we are missing is that we can never look to other people or things to give us what only God can provide.
When our relationship with God is first and His mission for our life is the ultimate measure of our success then all other relationships and endeavors play a secondary role and become complimentary and not primary.
Then when the pain, failure and rejection come in this life they can always be measured against the grace and peace that only God can give. The assurance that He will never leave us and nothing can separate us from His love gives us the courage to risk living life to the fullest.
In the end He is enough.